Annual report pursuant to Section 13 and 15(d)

Equity (Details)

v3.8.0.1
Equity (Details) - Stock Options [Member] - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Summary of stock option/ warrant activities      
Number of Units, Outstanding, Beginning 5,906,886 3,971,583 3,013,084
Number of Units, Granted 2,597,500 2,225,000 1,554,499
Number of Units, Cancelled (3,329,794) (266,485) (576,000)
Number of Units, Exercised   (23,212) (20,000)
Number of Units, Outstanding, Ending 5,174,592 5,906,886 3,971,583
Number of Units, Exercisable 2,415,632    
Weighted Average Exercise Price, Outstanding, Beginning $ 3.52 $ 4.34 $ 5.98
Weighted Average Exercise Price, Granted 1.32 1.92 2.78
Weighted Average Exercise Price, Cancelled 2.85 2.51 8.70
Weighted Average Exercise Price, Exercised   0.78 0.78
Weighted Average Exercise Price, Outstanding, Ending 2.83 $ 3.52 $ 4.34
Weighted Average Exercise Price, Exercisable $ 3.98    
Weighted Average Remaining Contractual Term (in years), Outstanding, Beginning 7 years 10 months 25 days 8 years 4 days 8 years 4 months 6 days
Weighted Average Remaining Contractual Term (in years), Outstanding, Ending 7 years 11 months 12 days 7 years 10 months 25 days 8 years 4 days
Weighted Average Remaining Contractual Term (in years), Exercisable 6 years 4 months 17 days    
Aggregate Intrinsic Value, Outstanding, Beginning $ 51,704 $ 2,964,146 $ 4,728,842
Aggregate Intrinsic Value, Outstanding, Ending 2,648 $ 51,704 $ 2,964,146
Aggregate Intrinsic Value, Exercisable