Annual report pursuant to Section 13 and 15(d)

Income Taxes (Details) - Schedule of difference between income tax provision and U.S federal statutory rates

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Income Taxes (Details) - Schedule of difference between income tax provision and U.S federal statutory rates - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Schedule of difference between income tax provision and U.S federal statutory rates [Abstract]    
Federal statutory income taxes $ (5,202) $ (4,665)
Federal statutory income taxes, percentage (21.00%) (21.00%)
State income taxes $ (373) $ 56
State income taxes, percentage (1.50%) 0.30%
Deferred true-up $ 562 $ (64)
Deferred true-up, percentage 2.30% (0.30%)
Research and development/orphan drug tax credit $ (1,898) $ (1,766)
Research and development/orphan drug tax credit, percentage (7.70%) (8.00%)
Other $ 486 $ 202
Other, percentage 2.00% 0.90%
Change in valuation allowance $ 6,425 $ 6,237
Change in valuation allowance, percentage 25.90% 28.10%
Provision for income tax
Provision for income tax, percentage