Annual report pursuant to Section 13 and 15(d)

Income Taxes (Details)

v3.22.1
Income Taxes (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Taxes (Details) [Line Items]    
Deferred tax assets, valuation allowance $ 62.6 $ 56.2
Federal income tax purposes, net operating losses $ 163.0  
Net operating losses, description NOLs of $120.8 million generated prior to 2018 will begin to expire if unused in 2022. NOLs generated in 2018 and later years of $42.2 million have an indefinite life, but will be limited to 80% of their value if used in a tax year ending after January 1, 2022.  
State income tax purposes, net operating losses   $ 87.9
Federal Research and Development Tax Credits [Member]    
Income Taxes (Details) [Line Items]    
Net operating loss expiration date The Company has federal research and development tax credits of $2.9 million at December 31, 2021 which will begin to expire in 2034 if unused and orphan drug credits of $11.6 million which will begin to expire in 2028 if unused.    
Net operating losses $ 2.9  
Orphan Drug Credits [Member]    
Income Taxes (Details) [Line Items]    
Net operating losses $ 11.6