Annual report pursuant to Section 13 and 15(d)

Equity (Details Textual)

v3.19.1
Equity (Details Textual) - USD ($)
1 Months Ended 12 Months Ended
Aug. 02, 2017
Oct. 04, 2016
Dec. 19, 2012
Oct. 18, 2018
Mar. 31, 2018
Aug. 02, 2017
Jun. 06, 2017
Mar. 14, 2017
Sep. 30, 2013
Jan. 31, 2012
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2013
Nov. 08, 2018
Equity (Textual)                                
Net proceeds from issuance of shares                       $ 3,800,000        
Stock based compensation expense                     $ 33,000 10,000 $ 10,000      
Warrant to purchase of common stock     57,212                          
Fair value of warrants                       300,000 2,500,000      
Net proceeds on exercise of warrants                     $ 4,849      
Employees options to purchase granted                     530,000          
Gross proceeds                         $ 18,105      
Additional non-cash expense incremental fair value               $ 64,000                
Restricted Stock [Member]                                
Equity (Textual)                                
Issuance of common stock, shares                         21,000      
Stock based compensation expense                     $ 10,000 $ 20,000 $ 60,000      
Number of shares of restricted stock, vested                     254,819          
Number of stock option/restricted shares canceled                       3,329,794        
Restricted common shares granted vested                     107,911          
Restricted common shares granted, value                     $ 72,825          
Restricted common shares granted fully vested                     156,393          
Restricted common shares granted fully vested, value                     $ 81,393          
Restricted stock granted, shares                         60,700      
Employee Stock Option [Member]                                
Equity (Textual)                                
Stock based compensation expense                     $ 2,600,000          
Fair value assumptions, expected life                     6 years 6 years 6 years      
Fair value assumptions, expected dividend rate                     0.00% 0.00% 0.00%      
Total option expense                     $ 1,700,000 $ 3,100,000 $ 3,600,000      
Number of stock option/restricted shares canceled                     1,515,650 3,329,794 266,485      
Number of stock option/warrants granted                     3,577,159 2,597,500 2,225,000      
Stock options, term                     10 years 10 years 10 years      
Stock options, vesting period                         4 years      
Fair value of stock options                     $ 1,700,000 $ 2,400,000 $ 3,100,000      
Gross proceeds                         $ 18,105      
Warrants exercised, shares                         23,212      
Director [Member]                                
Equity (Textual)                                
Fair value assumptions, expected dividend rate             0.00%                  
Total option expense             $ 174,000                  
Director left - option extension             Pursuant to the agreement, all the outstanding vested options, (which originally were to expire 90 days from termination date), as well as 68,200 unvested options granted prior to December 31, 2016, shall be exercisable until the end of the term of each option grant agreement.                  
Chairman [Member]                                
Equity (Textual)                                
Warrant to purchase of common stock                   64,746            
Chief Executive Officer [Member]                                
Equity (Textual)                                
Warrant to purchase of common stock                   99,617            
2013 Stock Plan [Member]                                
Equity (Textual)                                
Number of additional shares authorized                     22,750,000 17,750,000 12,750,000 9,250,000 1,000,000  
2013 Stock Plan [Member] | Employees, directors and consultants [Member]                                
Equity (Textual)                                
Number of stock option/warrants granted                 2,750,000              
Plan expiration date                 Sep. 09, 2023              
Employees, directors and consultants [Member] | Employees, directors and consultants [Member]                                
Equity (Textual)                                
Number of stock option/warrants granted                 450,000              
Plan expiration date                 Sep. 09, 2023              
Purchase Agreement [Member]                                
Equity (Textual)                                
Additional shares of common stock       852,537                        
Additional shares of common stock, value       $ 32,500,000                        
Fair value of market price       $ 600,000                        
Maximum [Member] | Employee Stock Option [Member]                                
Equity (Textual)                                
Fair value assumptions, expected discount rate                     2.28% 2.28% 1.28%      
Fair value assumptions, expected volatility rate                     80.40% 82.37% 81.45%      
Stock options, vesting period                     4 years 2 months 12 days 4 years 2 months 12 days        
Warrants exercise price                     $ 0.7829 $ 1.58 $ 2.25      
Fair value assumptions, expected discount rate                     0.0299 0.0228        
Maximum [Member] | Director [Member]                                
Equity (Textual)                                
Fair value assumptions, expected life             8 years 10 months 25 days                  
Fair value assumptions, expected discount rate             1.39%                  
Fair value assumptions, expected volatility rate             79.81%                  
Fair value assumptions, expected dividend rate             0.00%                  
Minimum [Member] | Employee Stock Option [Member]                                
Equity (Textual)                                
Fair value assumptions, expected discount rate                       1.84% 1.97%      
Fair value assumptions, expected volatility rate                     78.80% 80.83% 87.95%      
Stock options, vesting period                     4 years 4 years        
Warrants exercise price                     $ 0.344 $ 0.57 $ 0.95      
Fair value assumptions, expected discount rate                     0.0234 0.0184        
Minimum [Member] | Director [Member]                                
Equity (Textual)                                
Fair value assumptions, expected life             3 months                  
Fair value assumptions, expected discount rate             0.97%                  
Fair value assumptions, expected volatility rate             45.72%                  
Fair value assumptions, expected dividend rate             0.00%                  
Public offering [Member]                                
Equity (Textual)                                
Issuance of common stock, shares 21,500,000                              
Warrant to purchase of common stock 18,275,000                              
Net proceeds of public offering $ 15,000,000 $ 9,300,000                            
Offering price $ 0.75 $ 1.25       $ 0.75                    
Proceeds from common stock issued $ 16,100,000 $ 8,000,000                            
Warrants, vesting period 5 years                              
Warrants exercise price $ 1.05         $ 1.05                    
Warrant [Member]                                
Equity (Textual)                                
Underwritten offering common stock                     21,500,000          
Warrant to purchase of common stock 18,275,000                   18,275,000          
Fair value of warrants                     $ 27,000          
Number of warrant granted                     120,628          
Number of warrants issued to consultants                     120,628          
Number of stock option/restricted shares canceled                     194,598 1,789,623        
Number of stock option/warrants granted                     30,360,466 18,496,575 130,000      
Warrants exercise price                     $ 1.05          
Warrants exercised, shares                     7,332 9,364 183,718      
Warrant [Member] | Maximum [Member]                                
Equity (Textual)                                
Warrants exercise price                     $ 0.65          
Warrant [Member] | Minimum [Member]                                
Equity (Textual)                                
Warrants exercise price                     $ 0.36          
Stock Options [Member]                                
Equity (Textual)                                
Number of warrant granted                     3,565,159          
Fair value assumptions, expected life                     6 years          
Fair value assumptions, expected dividend rate                     0.00%          
Options to purchase common shares, cancelled                     1,100,000          
Total option expense                     $ 1,300,000 $ 2,500,000        
Number of stock option/restricted shares canceled                     1,515,650 3,329,794 266,485      
Number of stock option/warrants granted                     3,577,159 2,597,500 2,225,000      
Stock options, term                     10 years          
Stock options, vesting period                     4 years          
Fair value of stock options                     $ 1,700,000          
Warrants exercised, shares                         23,212      
Stock Options [Member] | Maximum [Member]                                
Equity (Textual)                                
Fair value assumptions, expected discount rate                     2.94%          
Fair value assumptions, expected volatility rate                     80.40%          
Stock Options [Member] | Minimum [Member]                                
Equity (Textual)                                
Fair value assumptions, expected discount rate                     2.34%          
Fair value assumptions, expected volatility rate                     79.10%          
Lincoln Park Capital Fund, LLC [Member]                                
Equity (Textual)                                
Additional shares of common stock       400,000                        
Additional shares of common stock, value       $ 30,000,000                        
Purchased shares of common stock       3,376,554                        
Purchased value of common stock       $ 2,500,000                        
Purchase of shares (will not exceed)       $ 1,500,000                        
Accelerated purchase, description       (i) 300% the number of shares purchased pursuant to the corresponding Regular Purchase or (ii) 30% of the total number of shares of the Company's common stock traded during a specified period on the applicable purchase date as set forth in the agreement.                        
Maximum beneficially owning, percentage       9.99%                        
Received amount                     $ 700,000          
Sales of aggregate of commonstock units                     1,000,000          
Offering price       $ 0.75                        
Consultants [Member]                                
Equity (Textual)                                
Common shares for consulting services, value                       $ 99,000        
Common shares for consulting services, shares                       67,385        
Share Price                       $ 1.47        
Consultants [Member] | Restricted Stock [Member]                                
Equity (Textual)                                
Common shares for consulting services, value                       $ 65,813        
Common shares for consulting services, shares                       59,393 250,700      
Restricted stock granted value                         $ 40,000      
Number of stock option/restricted shares canceled                       26,000        
Series A warrants [Member]                                
Equity (Textual)                                
Warrants exercisable period                     1 year          
Fair value of warrants                     $ 500,000          
Description of warrant exercisable         Each series A warrant exercisable for one share of common stock at an exercise price of $0.60 per share.                      
Fair value assumptions, expected life                     1 year          
Fair value assumptions, expected discount rate                     2.06%          
Fair value assumptions, expected volatility rate                     72.00%          
Fair value assumptions, expected dividend rate                     0.00%          
Aggregate series warrants         7,559,445                      
Warrants exercise price                     $ 0.60          
Series B warrants [Member]                                
Equity (Textual)                                
Net proceeds from issuance of shares         $ 13,800,000                      
Warrants exercisable period                     2 years 6 months          
Fair value of warrants                     $ 2,500,000          
Description of warrant exercisable         Each series B warrant exercisable for one share of common stock at an exercise price of $0.70 per share.                      
Fair value assumptions, expected life                     2 years 6 months          
Fair value assumptions, expected discount rate                     2.33%          
Fair value assumptions, expected volatility rate                     71.00%          
Fair value assumptions, expected dividend rate                     0.00%          
Gross proceeds         $ 15,100,000                      
Aggregate series warrants         22,678,393                      
Warrants exercise price                     $ 0.70          
Warrants [Member]                                
Equity (Textual)                                
Underwritten offering common stock           21,500,000                    
Warrant to purchase of common stock           18,275,000                    
Fair value of warrants           $ 4,900,000                    
Fair value assumptions, expected life           5 years                    
Fair value assumptions, expected discount rate           1.83%                    
Fair value assumptions, expected volatility rate           82.00%                    
Fair value assumptions, expected dividend rate           0.00%                    
Gross proceeds from warrants exercised           $ 20,400,000                    
Share Price $ 0.75         $ 0.75                    
Warrants exercise price $ 1.05         $ 1.05                    
Warrants [Member] | Mr. Sandesh Seth [Member]                                
Equity (Textual)                                
Warrants issued                               375,556
Warrants [Member] | Chairman [Member]                                
Equity (Textual)                                
Warrants issued                               353,023
Warrants [Member] | Chief Executive Officer [Member]                                
Equity (Textual)                                
Warrants issued                               721,068
Warrants [Member] | Maximum [Member]                                
Equity (Textual)                                
Fair value assumptions, expected life                       5 years 10 years      
Fair value assumptions, expected discount rate                       2.34% 1.13%      
Fair value assumptions, expected volatility rate                     79.00%   84.84%      
Warrants exercise price                       $ 0.36 $ 1.77      
Warrants exercisable term                         10 years      
Warrants [Member] | Minimum [Member]                                
Equity (Textual)                                
Fair value assumptions, expected life                       4 years 5 years      
Fair value assumptions, expected discount rate                       2.99% 1.20%      
Fair value assumptions, expected volatility rate                     77.01%   79.79%      
Warrants exercise price                       $ 0.80 $ 0.98      
Warrants [Member] | Consultants [Member]                                
Equity (Textual)                                
Fair value of warrants                       $ 27,000 $ 116,000      
Fair value assumptions, expected dividend rate                       0.00% 0.00%      
Number of stock option/warrants granted                       122,628 130,000      
Common Stock [Member]                                
Equity (Textual)                                
Sales of aggregate of commonstock units         30,237,894                      
Issuance of common stock, shares         30,237,894             2,672,973 3,500,000      
Net proceeds from issuance of shares                         $ 6,800,000      
Common shares issued for cashless exercise of warrants                       4,234 125,862      
Stock based compensation expense                       $ 200,000        
Net proceeds of public offering                       $ 4,000,000