Annual report pursuant to Section 13 and 15(d)

Equity (Details Textual)

Equity (Details Textual) - USD ($)				1 Months Ended							12 Months Ended
Equity (Details Textual) - USD ($)	Aug. 02, 2017	Oct. 04, 2016	Dec. 19, 2012	Oct. 18, 2018	Mar. 31, 2018	Aug. 02, 2017	Jun. 06, 2017	Mar. 14, 2017	Sep. 30, 2013	Jan. 31, 2012	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2013	Nov. 08, 2018
Equity (Textual)
Net proceeds from issuance of shares												$ 3,800,000
Stock based compensation expense											$ 33,000	10,000	$ 10,000
Warrant to purchase of common stock			57,212
Fair value of warrants												300,000	2,500,000
Net proceeds on exercise of warrants											$ 4,849
Employees options to purchase granted											530,000
Gross proceeds													$ 18,105
Additional non-cash expense incremental fair value								$ 64,000
Restricted Stock [Member]
Equity (Textual)
Issuance of common stock, shares													21,000
Stock based compensation expense											$ 10,000	$ 20,000	$ 60,000
Number of shares of restricted stock, vested											254,819
Number of stock option/restricted shares canceled												3,329,794
Restricted common shares granted vested											107,911
Restricted common shares granted, value											$ 72,825
Restricted common shares granted fully vested											156,393
Restricted common shares granted fully vested, value											$ 81,393
Restricted stock granted, shares													60,700
Employee Stock Option [Member]
Equity (Textual)
Stock based compensation expense											$ 2,600,000
Fair value assumptions, expected life											6 years	6 years	6 years
Fair value assumptions, expected dividend rate											0.00%	0.00%	0.00%
Total option expense											$ 1,700,000	$ 3,100,000	$ 3,600,000
Number of stock option/restricted shares canceled											1,515,650	3,329,794	266,485
Number of stock option/warrants granted											3,577,159	2,597,500	2,225,000
Stock options, term											10 years	10 years	10 years
Stock options, vesting period													4 years
Fair value of stock options											$ 1,700,000	$ 2,400,000	$ 3,100,000
Gross proceeds													$ 18,105
Warrants exercised, shares													23,212
Director [Member]
Equity (Textual)
Fair value assumptions, expected dividend rate							0.00%
Total option expense							$ 174,000
Director left - option extension							Pursuant to the agreement, all the outstanding vested options, (which originally were to expire 90 days from termination date), as well as 68,200 unvested options granted prior to December 31, 2016, shall be exercisable until the end of the term of each option grant agreement.
Chairman [Member]
Equity (Textual)
Warrant to purchase of common stock										64,746
Chief Executive Officer [Member]
Equity (Textual)
Warrant to purchase of common stock										99,617
2013 Stock Plan [Member]
Equity (Textual)
Number of additional shares authorized											22,750,000	17,750,000	12,750,000	9,250,000	1,000,000
2013 Stock Plan [Member] \| Employees, directors and consultants [Member]
Equity (Textual)
Number of stock option/warrants granted									2,750,000
Plan expiration date									Sep. 09, 2023
Employees, directors and consultants [Member] \| Employees, directors and consultants [Member]
Equity (Textual)
Number of stock option/warrants granted									450,000
Plan expiration date									Sep. 09, 2023
Purchase Agreement [Member]
Equity (Textual)
Additional shares of common stock				852,537
Additional shares of common stock, value				$ 32,500,000
Fair value of market price				$ 600,000
Maximum [Member] \| Employee Stock Option [Member]
Equity (Textual)
Fair value assumptions, expected discount rate											2.28%	2.28%	1.28%
Fair value assumptions, expected volatility rate											80.40%	82.37%	81.45%
Stock options, vesting period											4 years 2 months 12 days	4 years 2 months 12 days
Warrants exercise price											$ 0.7829	$ 1.58	$ 2.25
Fair value assumptions, expected discount rate											0.0299	0.0228
Maximum [Member] \| Director [Member]
Equity (Textual)
Fair value assumptions, expected life							8 years 10 months 25 days
Fair value assumptions, expected discount rate							1.39%
Fair value assumptions, expected volatility rate							79.81%
Fair value assumptions, expected dividend rate							0.00%
Minimum [Member] \| Employee Stock Option [Member]
Equity (Textual)
Fair value assumptions, expected discount rate												1.84%	1.97%
Fair value assumptions, expected volatility rate											78.80%	80.83%	87.95%
Stock options, vesting period											4 years	4 years
Warrants exercise price											$ 0.344	$ 0.57	$ 0.95
Fair value assumptions, expected discount rate											0.0234	0.0184
Minimum [Member] \| Director [Member]
Equity (Textual)
Fair value assumptions, expected life							3 months
Fair value assumptions, expected discount rate							0.97%
Fair value assumptions, expected volatility rate							45.72%
Fair value assumptions, expected dividend rate							0.00%
Public offering [Member]
Equity (Textual)
Issuance of common stock, shares	21,500,000
Warrant to purchase of common stock	18,275,000
Net proceeds of public offering	$ 15,000,000	$ 9,300,000
Offering price	$ 0.75	$ 1.25				$ 0.75
Proceeds from common stock issued	$ 16,100,000	$ 8,000,000
Warrants, vesting period	5 years
Warrants exercise price	$ 1.05					$ 1.05
Warrant [Member]
Equity (Textual)
Underwritten offering common stock											21,500,000
Warrant to purchase of common stock	18,275,000										18,275,000
Fair value of warrants											$ 27,000
Number of warrant granted											120,628
Number of warrants issued to consultants											120,628
Number of stock option/restricted shares canceled											194,598	1,789,623
Number of stock option/warrants granted											30,360,466	18,496,575	130,000
Warrants exercise price											$ 1.05
Warrants exercised, shares											7,332	9,364	183,718
Warrant [Member] \| Maximum [Member]
Equity (Textual)
Warrants exercise price											$ 0.65
Warrant [Member] \| Minimum [Member]
Equity (Textual)
Warrants exercise price											$ 0.36
Stock Options [Member]
Equity (Textual)
Number of warrant granted											3,565,159
Fair value assumptions, expected life											6 years
Fair value assumptions, expected dividend rate											0.00%
Options to purchase common shares, cancelled											1,100,000
Total option expense											$ 1,300,000	$ 2,500,000
Number of stock option/restricted shares canceled											1,515,650	3,329,794	266,485
Number of stock option/warrants granted											3,577,159	2,597,500	2,225,000
Stock options, term											10 years
Stock options, vesting period											4 years
Fair value of stock options											$ 1,700,000
Warrants exercised, shares													23,212
Stock Options [Member] \| Maximum [Member]
Equity (Textual)
Fair value assumptions, expected discount rate											2.94%
Fair value assumptions, expected volatility rate											80.40%
Stock Options [Member] \| Minimum [Member]
Equity (Textual)
Fair value assumptions, expected discount rate											2.34%
Fair value assumptions, expected volatility rate											79.10%
Lincoln Park Capital Fund, LLC [Member]
Equity (Textual)
Additional shares of common stock				400,000
Additional shares of common stock, value				$ 30,000,000
Purchased shares of common stock				3,376,554
Purchased value of common stock				$ 2,500,000
Purchase of shares (will not exceed)				$ 1,500,000
Accelerated purchase, description				(i) 300% the number of shares purchased pursuant to the corresponding Regular Purchase or (ii) 30% of the total number of shares of the Company's common stock traded during a specified period on the applicable purchase date as set forth in the agreement.
Maximum beneficially owning, percentage				9.99%
Received amount											$ 700,000
Sales of aggregate of commonstock units											1,000,000
Offering price				$ 0.75
Consultants [Member]
Equity (Textual)
Common shares for consulting services, value												$ 99,000
Common shares for consulting services, shares												67,385
Share Price												$ 1.47
Consultants [Member] \| Restricted Stock [Member]
Equity (Textual)
Common shares for consulting services, value												$ 65,813
Common shares for consulting services, shares												59,393	250,700
Restricted stock granted value													$ 40,000
Number of stock option/restricted shares canceled												26,000
Series A warrants [Member]
Equity (Textual)
Warrants exercisable period											1 year
Fair value of warrants											$ 500,000
Description of warrant exercisable					Each series A warrant exercisable for one share of common stock at an exercise price of $0.60 per share.
Fair value assumptions, expected life											1 year
Fair value assumptions, expected discount rate											2.06%
Fair value assumptions, expected volatility rate											72.00%
Fair value assumptions, expected dividend rate											0.00%
Aggregate series warrants					7,559,445
Warrants exercise price											$ 0.60
Series B warrants [Member]
Equity (Textual)
Net proceeds from issuance of shares					$ 13,800,000
Warrants exercisable period											2 years 6 months
Fair value of warrants											$ 2,500,000
Description of warrant exercisable					Each series B warrant exercisable for one share of common stock at an exercise price of $0.70 per share.
Fair value assumptions, expected life											2 years 6 months
Fair value assumptions, expected discount rate											2.33%
Fair value assumptions, expected volatility rate											71.00%
Fair value assumptions, expected dividend rate											0.00%
Gross proceeds					$ 15,100,000
Aggregate series warrants					22,678,393
Warrants exercise price											$ 0.70
Warrants [Member]
Equity (Textual)
Underwritten offering common stock						21,500,000
Warrant to purchase of common stock						18,275,000
Fair value of warrants						$ 4,900,000
Fair value assumptions, expected life						5 years
Fair value assumptions, expected discount rate						1.83%
Fair value assumptions, expected volatility rate						82.00%
Fair value assumptions, expected dividend rate						0.00%
Gross proceeds from warrants exercised						$ 20,400,000
Share Price	$ 0.75					$ 0.75
Warrants exercise price	$ 1.05					$ 1.05
Warrants [Member] \| Mr. Sandesh Seth [Member]
Equity (Textual)
Warrants issued																375,556
Warrants [Member] \| Chairman [Member]
Equity (Textual)
Warrants issued																353,023
Warrants [Member] \| Chief Executive Officer [Member]
Equity (Textual)
Warrants issued																721,068
Warrants [Member] \| Maximum [Member]
Equity (Textual)
Fair value assumptions, expected life												5 years	10 years
Fair value assumptions, expected discount rate												2.34%	1.13%
Fair value assumptions, expected volatility rate											79.00%		84.84%
Warrants exercise price												$ 0.36	$ 1.77
Warrants exercisable term													10 years
Warrants [Member] \| Minimum [Member]
Equity (Textual)
Fair value assumptions, expected life												4 years	5 years
Fair value assumptions, expected discount rate												2.99%	1.20%
Fair value assumptions, expected volatility rate											77.01%		79.79%
Warrants exercise price												$ 0.80	$ 0.98
Warrants [Member] \| Consultants [Member]
Equity (Textual)
Fair value of warrants												$ 27,000	$ 116,000
Fair value assumptions, expected dividend rate												0.00%	0.00%
Number of stock option/warrants granted												122,628	130,000
Common Stock [Member]
Equity (Textual)
Sales of aggregate of commonstock units					30,237,894
Issuance of common stock, shares					30,237,894							2,672,973	3,500,000
Net proceeds from issuance of shares													$ 6,800,000
Common shares issued for cashless exercise of warrants												4,234	125,862
Stock based compensation expense												$ 200,000
Net proceeds of public offering												$ 4,000,000