Quarterly report pursuant to Section 13 or 15(d)

Equity (Details Textual)

v3.19.3
Equity (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Apr. 30, 2019
Oct. 31, 2018
Mar. 31, 2018
Sep. 30, 2019
Sep. 30, 2018
Equity (Textual)          
Sales of common stock, shares 42,900,000   30,200,000 2,800,000  
Net proceeds on sale of common stock $ 15,100,000   $ 13,800,000 $ 800,000  
Common shares for consulting services, shares       400,000  
Net proceeds on exercise of warrants       $ 1,503,762 $ 4,849
Description of shares The Company sold 42.9 million shares of common stock at an offering price of $0.385 per share and warrants to purchase up to 42.9 million shares of common stock at an exercise price of $0.50 per share and with a term of 5 years, resulting in gross proceeds of $16.5 million and net proceeds of $15.1 million after deducting underwriting and other offering expenses.   In March 2018, the Company sold an aggregate of 30.2 million units consisting of an aggregate of 30.2 million shares of common stock, 7.6 million series A warrants and 22.7 million series B warrants, with each series A warrant exercisable for one share of Common Stock at an exercise price of $0.60 per share and each series B warrant exercisable for one share of Common Stock at an exercise price of $0.70 per share, resulting in gross proceeds of approximately $15.1 million (each unit was sold at $0.50 per unit), and net proceeds of approximately $13.8 million after deducting expenses relating to dealer-manager fees and other offering expenses.    
Stock Options [Member]          
Equity (Textual)          
Stock option granted to employees       5,738,500  
Option exercise price minimum       $ 0.223  
Option exercise price maximum       $ 0.58  
Warrants, description       The options have an aggregated fair value of $1.1 million that was calculated using the Black-Scholes option-pricing model. Variables used in the Black-Scholes option-pricing model include: (1) discount rate range from 1.38% to 2.60% (2) expected life of 6 years, (3) expected volatility range from 78.5% to 80.6%, and (4) no expected dividends. During the nine months ended September 30, 2019, options to purchase 1.0 million shares were cancelled upon the termination of employment for several employees.  
Total option expense       $ 900,000 1,300,000
Unrecognized compensation expense       $ 2,500,000  
Number of stock options canceled       1,042,800  
Stock options, term       10 years  
Stock options, vesting period       4 years  
Lincoln Park Capital Fund, LLC [Member]          
Equity (Textual)          
Received amount         $ 100,000
Sales of common stock, shares         400,000
Number of shares of restricted stock, vested         100,000
Lincoln Park Capital Fund, LLC [Member] | Purchase Agreement [Member]          
Equity (Textual)          
Net proceeds on sale of common stock   $ 32,500,000      
Warrants [Member]          
Equity (Textual)          
Warrants, description The transaction date relative fair value of the April 2019 warrants of $5.3 million was determined utilizing the Black-Scholes option pricing model and variables of (1) a discount rate of 2.35%, (2) expected term of 5 years, (3) expected volatility of 78% and (4) zero expected dividends.        
Description of warrants The Company has outstanding warrants to purchase 57,212 shares that include down-round protection. For warrants with down-round protection, a deemed dividend is recorded for the change in fair value of the warrants when the down-round provision is triggered. As result of the April 2019 offering, the exercise price of the warrant was reset from $1.25 per share to $0.88 per share. The down-round protection provision in the above warrants created a deemed dividend to common stockholders of $1,269, which is reflected in the accompanying consolidated statement of operations and consolidated statement of changes in stockholders' equity.        
Series A warrants [Member]          
Equity (Textual)          
Sales of common stock, shares     30,200,000    
Issuance of common stock, shares     30,200,000    
Warrants exercised by warrant holders       2,500,000  
Weighted average remaining contractual term       3 years 4 months 24 days  
Series B warrants [Member]          
Equity (Textual)          
Description of warrant exercisable         Each series B warrant exercisable for one share of Common Stock at an exercise price of $0.70 per share.
Aggregate series warrants     22,700,000