Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies (Details Textual)

v3.5.0.2
Commitments and Contingencies (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Aug. 04, 2016
Feb. 27, 2014
Jul. 24, 2012
Aug. 31, 2016
Dec. 21, 2015
Apr. 22, 2014
Jun. 15, 2012
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Feb. 16, 2016
Dec. 31, 2015
Sep. 30, 2014
Commitments and Contingencies (Textual)                            
Research recorded fees               $ 5,685,777 $ 2,828,093 $ 13,599,174 $ 10,714,766      
Letter of credit           $ 34,733                
Sub lease agreement expiration date           Sep. 30, 2016                
Cost of lease agreement       $ 2,400           16,620        
Manufacturing Agreement [Member]                            
Commitments and Contingencies (Textual)                            
Project estimated cost   $ 5,700,000               1,900,000        
Non - refundable institutional fee   $ 600,000                        
Total project estimated to cost               100,000   100,000     $ 100,000  
Research and development costs                   500,000 3,900,000      
Einstein [Member]                            
Commitments and Contingencies (Textual)                            
Total project estimated to cost               200,000   200,000       $ 200,000
Research and development costs                   37,000 55,000      
CRO Agreement [Member]                            
Commitments and Contingencies (Textual)                            
Project estimated cost $ 4,600,000                 700,000        
AbbVie Biotherapeutics Corp [Member] | Product Development and Patent License Agreement [Member]                            
Commitments and Contingencies (Textual)                            
License fee payment                   3,000,000        
Milestones payments                   $ 7,750,000        
Description of royalty payment                   The Company shall pay to AbbVie Biotherapeutics Corp. on a country-by-country basis a royalty of 12% of net sales of all licensed products until the later of: (1) 12.5 years after the first commercial sale, or (2) when the patents expire.        
Royalty of net sales percentage                   12.00%        
First commercial sale period                   12 years 6 months        
AbbVie Biotherapeutics Corp [Member] | After first net sales [Member]                            
Commitments and Contingencies (Textual)                            
Milestones payments                   $ 1,500,000        
AbbVie Biotherapeutics Corp [Member] | Phase 1 Clinical Trial of a licensed product [Member]                            
Commitments and Contingencies (Textual)                            
Milestones payments     $ 750,000             750,000        
Abbott Biotherapeutics Corp [Member] | After first net sales [Member] | Product Development and Patent License Agreement [Member]                            
Commitments and Contingencies (Textual)                            
Net sales in milestones payment                   10,000,000        
Oak Ridge National Laboratory [Member]                            
Commitments and Contingencies (Textual)                            
Research and development costs         $ 900,000         $ 300,000 200,000      
Icon Clinical Research [Member]                            
Commitments and Contingencies (Textual)                            
Down payment of project estimated cost percentage                   12.50%        
Down payment for project                   $ 1,900,000        
Down payment paid in 2007 and 2012                   200,000        
Total project estimated to cost               $ 2,700,000   2,700,000        
Research and development costs                   $ 500,000 400,000      
Fred Hutchinson Cancer Research Center [Member] | license and sponsored research agreement [Member]                            
Commitments and Contingencies (Textual)                            
Milestones payments             $ 1,000,000              
Description of royalty payment                   Royalty payments of 2% of net sales will be due to FHCRC.        
Fund for Fred Hutchinson Cancer Research Center lab ( Per year for the first two years )             200,000              
Fund for Fred Hutchinson Cancer Research Center lab ( thereafter )             300,000              
Research recorded fees                   $ 400,000 $ 200,000      
Fred Hutchinson Cancer Research Center [Member] | Maximum [Member] | license and sponsored research agreement [Member]                            
Commitments and Contingencies (Textual)                            
Clinical trial cost for approval of food and drug administration             30,000,000              
Fred Hutchinson Cancer Research Center [Member] | Minimum [Member] | license and sponsored research agreement [Member]                            
Commitments and Contingencies (Textual)                            
Clinical trial cost for approval of food and drug administration             $ 25,000,000              
Medpace, Inc. [Member] | CRO Agreement [Member]                            
Commitments and Contingencies (Textual)                            
Total project estimated to cost                       $ 7,200,000    
Research and development costs                   $ 2,600,000