Annual report [Section 13 and 15(d), not S-K Item 405]

Income Taxes (Details)

v3.25.1
Income Taxes (Details) - USD ($)
$ in Thousands
12 Months Ended
Jan. 01, 2023
Dec. 31, 2024
Dec. 31, 2023
Income Taxes [Line Items]      
Valuation allowance   $ 101,613 $ 90,565
Unused net operating losses   327,800  
Net operating losses   104,800  
Indefinite life   84,600  
Net operating loss percentage 80.00%    
Federal research and development tax credits   20,664 $ 18,684
Research and development costs   28,000  
Accumulated gross amount   87,900  
Federal income tax [Member]      
Income Taxes [Line Items]      
Unused net operating losses   189,300  
Net operating losses due to expire in 2026 [Member]      
Income Taxes [Line Items]      
Net operating losses   3,900  
Net operating losses expire in 2034 - 2037 [Member]      
Income Taxes [Line Items]      
Net operating losses   15,000  
Tax Year 2033 [Member]      
Income Taxes [Line Items]      
Federal research and development tax credits   6,700  
Tax Year 2037 [Member] | Orphan Drug Credits [Member]      
Income Taxes [Line Items]      
Federal research and development tax credits   $ 16,500