Annual report pursuant to Section 13 and 15(d)

Income Taxes (Details)

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Income Taxes (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Income Taxes [Line Items]    
Deferred tax assets, valuation allowance $ 90.6 $ 76.1
Federal income tax, net operating losses 165.1  
Net operating losses 104.8  
indefinite life $ 60.3  
Description of limitation of net loss limited to 80% of their value if used in a tax year ending after January 1, 2023.  
State income tax, net operating losses $ 283.0  
research and development costs 36.9  
Accumulated gross amount 79.6  
Orphan Drug Credits [Member]    
Income Taxes [Line Items]    
Federal research and development tax credits 15.4  
2024 [Member]    
Income Taxes [Line Items]    
Net operating losses 3.9  
2034 - 2037 [Member]    
Income Taxes [Line Items]    
Net operating losses $ 15.0  
UNITED STATES    
Income Taxes [Line Items]    
Expenditure capitalized under TCJA 5 years  
Non-US [Member]    
Income Taxes [Line Items]    
Expenditure capitalized under TCJA 15 years  
Federal Research and Development Tax Credits [Member] | Orphan Drug Credits [Member]    
Income Taxes [Line Items]    
Federal research and development tax credits $ 5.1