FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  CICIC DRAGAN
2. Date of Event Requiring Statement (Month/Day/Year)
12/28/2012
3. Issuer Name and Ticker or Trading Symbol
Cactus Ventures, Inc. [CTVN]
(Last)
(First)
(Middle)
501 FIFTH AVE, 3RD FL
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
COO and CMO
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10017
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 0
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Options to purchase common stock   (1) 10/26/2016 Options 48,485 $ 0.784 D  
Options to purchase common stock   (2) 11/28/2017 Options 33,300 $ 0.784 D  
Options to purchase common stock   (3) 02/10/2022 Options 333,000 $ 0.784 D  
Options to purchase common stock   (4) 08/30/2022 Options 99,900 $ 1.5 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
CICIC DRAGAN
501 FIFTH AVE, 3RD FL
NEW YORK, NY 10017
      COO and CMO  

Signatures

/s/ Dragan Cicic 01/02/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Options granted on October 26, 2006 to purchase an aggregate of 48,485 shares of common stock. Options vested 100%.
(2) Options granted on November 28, 2007 to purchase an aggregate of 33,300 shares of common stock. Options vested 100%.
(3) Options granted on February 10, 2012 to purchase an aggregate of 333,000 shares of common stock. Options vest at a rate of 2% per month. As of the date of this report, 73,260 options have vested pursuant to the February 10, 2012 grant.
(4) Options granted on August 30, 2012 to purchase an aggregate of 99,900 shares of common stock. Options vest at a rate of 2% per month. As of the date of this report, 7,992 options have vested pursuant to the August 30, 2012 grant.

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